Description

1,8-Naphthyridine-2-Acetic Acid,5,6,7,8-Tetrahydro-,Ethyl Ester is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmacologically active molecules, particularly within medicinal chemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of complex nitrogen-containing heterocycles for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing libraries of compounds in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its complex heterocyclic structure.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for the construction of complex polycyclic systems and functionalized naphthyridine derivatives.
• Ligand and Catalyst Development: Potential use in the design of novel chelating ligands for metal catalysis or in materials science applications.

Basic Information

Product Name	1,8-Naphthyridine-2-Acetic Acid,5,6,7,8-Tetrahydro-,Ethyl Ester
CAS No.	721920-80-5
Molecular Formula	C13H16N2O2
Molecular Weight	232.28 g/mol
Synonyms	Ethyl 5,6,7,8-tetrahydro-1,8-naphthyridine-2-acetate; 2-(Ethoxycarbonylmethyl)-5,6,7,8-tetrahydro-1,8-naphthyridine; 5,6,7,8-Tetrahydro-1,8-naphthyridine-2-acetic acid ethyl ester; THNE; Tetrahydro-1,8-naphthyridine ethyl acetate derivative
EINECS	Contact for details

Quality Control

Our 1,8-Naphthyridine-2-Acetic Acid,5,6,7,8-Tetrahydro-,Ethyl Ester is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong alkali and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.