Description

(S)-3-Amino-3-(3-Trifluoromethyl-Phenyl)-Propionic Acid CAS NO 719995-40-1 is a high-value, non-proteinogenic amino acid derivative featuring a chiral center and a trifluoromethylphenyl group. This compound matters as a critical chiral building block in modern pharmaceutical synthesis, where its structural motifs are leveraged to enhance drug potency, metabolic stability, and bioavailability. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disease targets.

Application

• As a key chiral intermediate in the synthesis of pharmaceutical candidates and active pharmaceutical ingredients (APIs).
• For research and development of peptidomimetics and bioactive peptides where its unnatural amino acid structure confers specific properties.
• In medicinal chemistry for constructing compound libraries aimed at drug discovery programs, especially for neurological and psychiatric disorders.
• As a precursor for the synthesis of more complex molecules requiring a trifluoromethylated phenylalanine analog.
• Use in asymmetric synthesis methodologies and catalysis studies due to its defined stereochemistry.
• Potential application in the development of diagnostic agents or imaging probes utilizing the fluorine atoms.

Basic Information

Product Name	(S)-3-Amino-3-(3-Trifluoromethyl-Phenyl)-Propionic Acid
CAS No.	719995-40-1
Molecular Formula	C10H10F3NO2
Molecular Weight	233.19 g/mol
Synonyms	(S)-3-Amino-3-(3-(trifluoromethyl)phenyl)propanoic acid; (S)-3-Amino-3-(α,α,α-trifluoro-m-tolyl)propionic acid; (S)-3-Amino-3-(m-trifluoromethylphenyl)propionic acid; (S)-β-Amino-β-(3-trifluoromethylphenyl)propionic acid; (S)-3-(3-Trifluoromethylphenyl)-3-aminopropanoic acid; (S)-3-(3-Trifluoromethylphenyl)-β-alanine; (S)-3-Amino-3-(3-trifluoromethylphenyl)propanoate
EINECS	Contact for details

Quality Control

Our (S)-3-Amino-3-(3-Trifluoromethyl-Phenyl)-Propionic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.