Description

Spiro[2.5]Oct-4-Ene-5-Carboxylic Acid, 8-Hydroxy-4,8-Dimethyl-6-Oxo-, Methyl Ester (9Ci) is a high-value, structurally complex organic compound featuring a unique spirocyclic framework combined with multiple functional groups, including carboxylic acid ester, ketone, and hydroxyl moieties. This intricate molecular architecture makes it a critical advanced intermediate for synthesizing novel pharmacologically active molecules and specialized fine chemicals. It is primarily sought after by research institutions and pharmaceutical R&D departments engaged in developing new therapeutic agents, particularly in areas requiring complex chiral scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially for central nervous system (CNS) and anti-inflammatory targets.
• Organic Synthesis Research: Used as a sophisticated starting material or intermediate in academic and industrial research exploring new chemical reactions and methodologies.
• Agrochemical Development: Potential intermediate for creating new active ingredients with complex molecular structures for crop protection.
• Material Science Precursor: Can be utilized in the development of specialty polymers or organic electronic materials due to its rigid, functionalized core.
• Asymmetric Catalysis Studies: The chiral centers and complex structure make it a valuable substrate for testing and developing new chiral catalysts and ligands.

Basic Information

Product Name	Spiro[2.5]Oct-4-Ene-5-Carboxylic Acid, 8-Hydroxy-4,8-Dimethyl-6-Oxo-, Methyl Ester (9Ci)
CAS No.	716381-20-3
Molecular Formula	C12H16O4
Molecular Weight	224.25 g/mol
Synonyms	Methyl 8-hydroxy-4,8-dimethyl-6-oxospiro[2.5]oct-4-ene-5-carboxylate; 8-Hydroxy-4,8-dimethyl-6-oxospiro[2.5]oct-4-ene-5-carboxylic acid methyl ester; Spiro[2.5]oct-4-ene-5-carboxylic acid, 8-hydroxy-4,8-dimethyl-6-oxo-, methyl ester; (9CI); CAS 716381-20-3
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC-MS, and NMR to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP-compliant manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be sensitive to prolonged exposure to heat, moisture, and strong light. Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.