Description

5,9-Methano-1H-Benzocycloheptene-1,9(2H)-Diol,Octahydro-,(1R,4As,5R,9R,9Ar)-Rel-(9Ci) is a high-purity, stereochemically defined synthetic intermediate of significant interest in advanced organic synthesis. Its complex, rigid polycyclic structure makes it a valuable chiral building block for constructing sophisticated molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and fine chemical industries for applications in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Asymmetric Synthesis: Utilized as a sophisticated chiral scaffold or ligand precursor in catalytic asymmetric reactions to induce high enantioselectivity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and library synthesis for drug discovery programs.
• Fine Chemical Production: Acts as a building block for the manufacture of specialty chemicals, fragrances, and advanced materials requiring specific stereochemistry.
• Academic & Industrial R&D: Used in methodological development and synthetic route exploration within university and corporate research laboratories.

Basic Information

Product Name	5,9-Methano-1H-Benzocycloheptene-1,9(2H)-Diol,Octahydro-,(1R,4As,5R,9R,9Ar)-Rel-(9Ci)
CAS No.	716380-78-8
Molecular Formula	C14H22O2
Molecular Weight	222.33 g/mol
Synonyms	(1R,4aS,5R,9R,9aR)-Octahydro-1,9-dihydroxy-5,9-methano-1H-benzocycloheptene; rel-(1R,4aS,5R,9R,9aR)-Octahydro-1,9-dihydroxy-5,9-methano-1H-benzocycloheptene; 5,9-Methanobenzocycloheptene-1,9-diol, octahydro-, (1R,4aS,5R,9R,9aR)-rel-; 716380-78-8; Chiral Octahydro-5,9-methanobenzocycloheptenediol; (rel)-(1R,4aS,5R,9R,9aR)-1,9-Dihydroxyoctahydro-5,9-methano-1H-benzocycloheptene
EINECS	Contact for details

Quality Control

Every batch of 5,9-Methano-1H-Benzocycloheptene-1,9(2H)-Diol,Octahydro-,(1R,4As,5R,9R,9Ar)-Rel-(9Ci) is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and stereochemical integrity, typically including chiral HPLC analysis. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.