Description

2‐Carbamoylcyclopropane‐1‐Carboxylic Acid is a high-purity, functionalized cyclopropane derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and valuable building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, including protease inhibitors and other bioactive molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with unique modes of action derived from the strained cyclopropane ring.
• Fine Chemical Synthesis: Serves as a precursor for specialty chemicals, ligands for catalysis, and advanced materials requiring rigid, three-carbon frameworks.
• Peptidomimetics & Conformationally Restricted Analogs: The cyclopropane ring is employed to constrain peptide backbones, enhancing metabolic stability and biological activity.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry, including studies on ring-opening and functionalization reactions.

Basic Information

Product Name	2‐Carbamoylcyclopropane‐1‐Carboxylic Acid
CAS No.	716362-29-7
Molecular Formula	C5H7NO3
Molecular Weight	129.11 g/mol
Synonyms	1-Carboxy-2-carbamoylcyclopropane; Cyclopropane-1,2-dicarboxamide, 1-carboxylic acid; 2-Carbamoylcyclopropanecarboxylic Acid; 1-Carbamoylcyclopropane-2-carboxylic Acid; (1R,2S)-rel-2-Carbamoylcyclopropanecarboxylic Acid (for chiral forms); Cyclopropanedicarboxylic acid monoamide; 2-Aminocarbonylcyclopropane-1-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 2‐Carbamoylcyclopropane‐1‐Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product may be hygroscopic; keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.