Description

D-Alanine, n-[(1,1-Dimethylethoxy)Carbonyl]-, Hydrazide (9Ci) is a specialized Boc-protected amino acid derivative, serving as a crucial chiral building block in advanced organic synthesis. Its primary value lies in enabling the controlled introduction of the D-alanine moiety into peptide chains and other complex molecules, which is essential for creating specific stereochemistry and biological activity. This high-purity intermediate is indispensable for researchers and manufacturers in pharmaceutical development, particularly for the synthesis of novel active pharmaceutical ingredients (APIs), peptide-based therapeutics, and diagnostic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel antibiotics, enzyme inhibitors, and peptide-based drugs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate D-alanine residues, which can enhance metabolic stability and alter biological activity.
• Proteomics Research: Employed in the design and synthesis of peptide probes, substrates, and inhibitors for biochemical and pharmacological studies.
• Chemical Biology: Serves as a building block for creating modified peptides and peptidomimetics to study protein-protein interactions and signaling pathways.
• Agrochemical Development: Potential use in the synthesis of chiral active ingredients for crop protection products.
• Academic & R&D: A valuable reagent for methodological development in asymmetric synthesis and for exploring new chemical entities in university and industrial research labs.

Basic Information

Product Name	D-Alanine, n-[(1,1-Dimethylethoxy)Carbonyl]-, Hydrazide (9Ci)
CAS No.	716329-42-9
Molecular Formula	C8H17N3O3
Molecular Weight	203.24 g/mol
Synonyms	Boc-D-Ala-NHNH2; Nα-Boc-D-alanine hydrazide; tert-Butoxycarbonyl-D-alanine hydrazide; D-Alanine, N-[(1,1-dimethylethoxy)carbonyl]-, hydrazide; Boc-D-Alanine hydrazide; (2R)-2-[(tert-Butoxycarbonyl)amino]propanehydrazide; N-Boc-D-alaninyl hydrazide
EINECS	Contact for details

Quality Control

Our D-Alanine, n-[(1,1-Dimethylethoxy)Carbonyl]-, Hydrazide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to meet the stringent requirements of pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.