Description

1H-Imidazole-1-Carboxylic Acid, 4-Nitro-, 1,1-Dimethylethyl Ester is a specialized, high-purity chemical building block primarily used in advanced organic synthesis. This compound is valued for its role as a versatile reagent in the formation of complex molecular architectures, particularly in pharmaceutical research and development. It is essential for chemists and manufacturers in the life sciences, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for constructing active pharmaceutical ingredients (APIs) and other functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly those containing imidazole or related heterocyclic cores.
• Peptide Coupling Reagent: Used in peptide synthesis as a protected or activated ester derivative for forming amide bonds under mild conditions.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced fungicides, herbicides, and plant growth regulators.
• Material Science Research: Employed in the creation of functional polymers, ligands for catalysis, and organic electronic materials.
• Bioconjugation Chemistry: Useful for labeling biomolecules or modifying surfaces in diagnostic and biochemical research applications.
• Academic & R&D Laboratories: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	1H-Imidazole-1-Carboxylic Acid, 4-Nitro-, 1,1-Dimethylethyl Ester
CAS No.	716316-20-0
Molecular Formula	C9H13N3O4
Molecular Weight	227.22 g/mol
Synonyms	4-Nitro-1H-imidazole-1-carboxylic acid tert-butyl ester; tert-Butyl 4-nitro-1H-imidazole-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-nitroimidazole; 4-Nitro-1-[(2-methyl-2-propanyl)oxycarbonyl]-1H-imidazole; Boc-4-nitroimidazole; 1-Boc-4-nitroimidazole; 4-Nitroimidazole-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 1H-Imidazole-1-Carboxylic Acid, 4-Nitro-, 1,1-Dimethylethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.