Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-8-Methoxy-7-[3-Methyl-4-[(Phenylamino)Thioxomethyl]-1-Piperazinyl]-4-Oxo- is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound is valued for its role as a key synthetic precursor in the development of novel antibacterial agents, particularly within the fluoroquinolone class. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of next-generation antibiotics and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel fluoroquinolone antibiotics.
• Antibacterial Drug Research: Used in R&D for developing new antibacterial agents targeting resistant bacterial strains.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a key precursor in multi-step synthesis processes for final drug substances.
• Chemical Reference Standard: Utilized as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.
• Medicinal Chemistry Studies: Employed in structure-activity relationship (SAR) studies to optimize antibacterial efficacy and safety profiles.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-8-Methoxy-7-[3-Methyl-4-[(Phenylamino)Thioxomethyl]-1-Piperazinyl]-4-Oxo-
CAS No.	714931-70-1
Molecular Formula	C24H25FN4O4S
Molecular Weight	476.55 g/mol
Synonyms	1-Cyclopropyl-6-fluoro-8-methoxy-7-[3-methyl-4-(phenylcarbamothioyl)piperazin-1-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; Garenoxacin Intermediate; Garenoxacin Carboxylic Acid; AM-1155 Intermediate; T-3811 Intermediate; 7-(3-Methyl-4-(phenylcarbamothioyl)piperazin-1-yl)-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards suitable for pharmaceutical R&D and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.