Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-8-Methoxy-7-[3-Methyl-4-[[(Phenylmethyl)Amino]Thioxomethyl]-1-Piperazinyl]-4-Oxo- is a high-purity, structurally complex organic compound designed for advanced pharmaceutical research and development. This compound serves as a critical advanced pharmaceutical intermediate (API intermediate) in the synthesis of novel therapeutic agents. It is essential for research organizations and manufacturers focused on developing next-generation pharmaceuticals, particularly in the fields of anti-infective and antibacterial agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel quinolone and fluoroquinolone-based active pharmaceutical ingredients (APIs).
• Antibacterial Drug Research: Used in R&D for developing new antibacterial compounds targeting resistant bacterial strains.
• Chemical Synthesis: Serves as a versatile precursor for further chemical modifications in medicinal chemistry programs.
• Process Development: Employed in scaling up and optimizing synthetic routes for potential drug candidates in pilot plants.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Academic & Institutional Research: Supports fundamental research in heterocyclic chemistry and drug discovery at universities and research institutes.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-8-Methoxy-7-[3-Methyl-4-[[(Phenylmethyl)Amino]Thioxomethyl]-1-Piperazinyl]-4-Oxo-
CAS No.	714918-68-0
Molecular Formula	C26H28FN5O4S
Molecular Weight	525.60 g/mol
Synonyms	1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[3-methyl-4-[[(phenylmethyl)amino]thioxomethyl]-1-piperazinyl]-4-oxo-3-quinolinecarboxylic acid; 7-(4-(Benzylcarbamothioyl)-3-methylpiperazin-1-yl)-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; GSK-2140944 Intermediate; GSK2140944 Intermediate; Benzyl 4-(1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carbonyl)-2-methylpiperazine-1-carbimidothioate; Advanced Fluoroquinolone Intermediate; API Intermediate 714918-68-0
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each batch to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.