Description

n-{3-[(3-Bromophenyl)Amino]Quinoxalin-2-Yl}Thiophene-2-Sulfonamide CAS NO 714917-90-5 is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry research and development. Pharmaceutical companies, contract research organizations (CROs), and academic research institutions engaged in drug discovery for oncology, neurology, and other therapeutic areas are the primary users of this specialized chemical.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of potential drug candidates, particularly those targeting kinase inhibition.
• Medicinal Chemistry Research: Used by R&D scientists for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Probe Development: Acts as a core scaffold for developing selective probes to study specific enzyme functions and cellular pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up synthesis under cGMP conditions for clinical trial material production.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and bioorganic chemistry.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) against novel biological targets.

Basic Information

Product Name	n-{3-[(3-Bromophenyl)Amino]Quinoxalin-2-Yl}Thiophene-2-Sulfonamide
CAS No.	714917-90-5
Molecular Formula	C18H13BrN4O2S2
Molecular Weight	477.36 g/mol
Synonyms	3-[(3-Bromophenyl)amino]-N-(thiophen-2-ylsulfonyl)quinoxalin-2-amine; 3-[(3-Bromoanilino)]-N-(2-thienylsulfonyl)quinoxalin-2-amine; 714917-90-5; N-(3-((3-Bromophenyl)amino)quinoxalin-2-yl)thiophene-2-sulfonamide; Quinoxaline-2-amine, 3-[(3-bromophenyl)amino]-N-(2-thienylsulfonyl)-; BPTQS; Thiophene-2-sulfonamide, N-[3-[(3-bromophenyl)amino]-2-quinoxalinyl]-
EINECS	Contact for details

Quality Control

Our n-{3-[(3-Bromophenyl)Amino]Quinoxalin-2-Yl}Thiophene-2-Sulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.