Description

4,6,7-Isoquinolinetriol,1,2,3,4-Tetrahydro-1,2-Dimethyl-,(1R,4S)-Rel-(9Ci) is a high-purity, stereochemically defined isoquinoline derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound, with CAS number 714905-74-5, serves as a sophisticated chiral building block for the development of novel bioactive molecules and complex natural product analogs. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for programs targeting neurological and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Natural Product Synthesis: Serves as a precursor in the total synthesis of complex alkaloids and other natural products with biological activity.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme inhibition and receptor binding mechanisms.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions.
• Academic Research: Used in university and institutional labs for advanced organic chemistry studies and methodology development.

Basic Information

Product Name	4,6,7-Isoquinolinetriol,1,2,3,4-Tetrahydro-1,2-Dimethyl-,(1R,4S)-Rel-(9Ci)
CAS No.	714905-74-5
Molecular Formula	C11H15NO3
Molecular Weight	209.24 g/mol
Synonyms	(1R,4S)-rel-1,2-Dimethyl-1,2,3,4-tetrahydro-4,6,7-isoquinolinetriol; 1,2,3,4-Tetrahydro-1,2-dimethyl-4,6,7-isoquinolinetriol, (1R,4S)-rel-; 4,6,7-Trihydroxy-1,2-dimethyl-1,2,3,4-tetrahydroisoquinoline (relative (1R,4S) configuration); Tetrahydroisoquinolinetriol derivative; Chiral tetrahydroisoquinoline scaffold
EINECS	Contact for details

Quality Control

Our 4,6,7-Isoquinolinetriol,1,2,3,4-Tetrahydro-1,2-Dimethyl-,(1R,4S)-Rel-(9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity (typically ≥95% by HPLC), chiral purity, and impurity profiles. We adhere to cGMP principles for research chemicals, and specifications can be customized to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a cool, dry, and well-ventilated place. The compound may be hygroscopic (moisture-sensitive); therefore, containers should be sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.