Description

3-(3-Bromo-Phenyl)-4,5-Dihydro-Isoxazole-5-Carboxylic Acid is a high-value brominated isoxazoline carboxylic acid derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in providing a versatile scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromophenyl and isoxazoline functionalities into target molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the bioactivity of the isoxazoline ring system.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating molecular probes to study enzyme function and biological pathways.
• Material Science: Potential monomer or additive for synthesizing specialized polymers with unique thermal or optical properties.
• Academic & Contract Research: Fundamental reagent for methodological development and exploratory synthesis in university and CRO laboratories.

Basic Information

Item	Detail
Product Name	3-(3-Bromo-Phenyl)-4,5-Dihydro-Isoxazole-5-Carboxylic Acid
CAS No.	712347-61-0
Molecular Formula	C10H8BrNO3
Molecular Weight	270.08 g/mol
Synonyms	5-Isoxazolecarboxylic acid, 4,5-dihydro-3-(3-bromophenyl)-; 3-(3-Bromophenyl)-4,5-dihydroisoxazole-5-carboxylic acid; 3-(3-Bromophenyl)-2-isoxazoline-5-carboxylic acid; 3-(3-Bromophenyl)-4,5-dihydro-1,2-oxazole-5-carboxylic acid; 3-(3-Bromophenyl)-δ²-isoxazoline-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-(3-Bromo-Phenyl)-4,5-Dihydro-Isoxazole-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the stringent requirements for research and development use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Ensure the storage area is well-ventilated.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.