Description

(3R)-3-Amino-3-[4-(Trifluoromethoxy)Phenyl]Propanoic Acid CAS NO 712321-33-0 is a high-purity, non-natural amino acid derivative featuring a chiral center and a trifluoromethoxy phenyl group. This compound is a critical chiral building block in modern pharmaceutical research and development, valued for its ability to impart metabolic stability and influence the physicochemical properties of drug candidates. It is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disease targets.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel Active Pharmaceutical Ingredients (APIs).
• Peptidomimetics & Drug Discovery: Used to incorporate non-natural amino acid motifs into peptide-based drug candidates to enhance stability and bioavailability.
• Medicinal Chemistry Research: Serves as a versatile building block for constructing compound libraries in high-throughput screening (HTS) campaigns.
• Agrochemical Synthesis: Potential intermediate in the development of advanced herbicides or pesticides with improved efficacy.
• Ligand & Catalyst Development: Can be utilized in the synthesis of chiral ligands for asymmetric catalysis.
• Chemical Biology Probes: Employed in the design of molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	(3R)-3-Amino-3-[4-(Trifluoromethoxy)Phenyl]Propanoic Acid
CAS No.	712321-33-0
Molecular Formula	C10H10F3NO3
Molecular Weight	249.19 g/mol
Synonyms	(R)-3-Amino-3-(4-(trifluoromethoxy)phenyl)propanoic acid; (3R)-3-Amino-3-[4-(trifluoromethoxy)phenyl]propionic acid; β-Amino-4-(trifluoromethoxy)benzenepropanoic acid (R)-; D-3-Amino-3-(4-trifluoromethoxyphenyl)propionic acid; (R)-3-Amino-3-(4-trifluoromethoxyphenyl)propanoic acid; 712321-33-0; 3-Amino-3-(4-(trifluoromethoxy)phenyl)propanoic acid (R)-
EINECS	Contact for details

Quality Control

Our (3R)-3-Amino-3-[4-(Trifluoromethoxy)Phenyl]Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if possible to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.