Description

Spiro[Cyclopentane-1,3-[1H,3H]Pyrrolo[1,2-C]Oxazole] (9Ci) is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic molecular architecture. This compound is of significant value in modern organic synthesis, serving as a critical building block for constructing complex molecular frameworks with precise stereochemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, especially for neurological and psychiatric disorders.
• Organic Synthesis Building Block: Utilized in complex multi-step syntheses to introduce spirocyclic motifs, which are valuable for modulating the physicochemical and biological properties of target molecules.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and library synthesis for hit-to-lead optimization in drug discovery programs.
• Asymmetric Catalysis Substrate: Serves as a substrate for developing and testing new asymmetric synthetic methodologies due to its defined stereogenic centers.
• Chemical Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	Spiro[Cyclopentane-1,3-[1H,3H]Pyrrolo[1,2-C]Oxazole] (9Ci)
CAS No.	706791-71-1
Molecular Formula	C9H13NO
Molecular Weight	151.21 g/mol
Synonyms	Spiro(cyclopentane-1,3'-pyrrolo[1,2-c]oxazole); 1H,3H-Spiro[cyclopentane-1,3'-pyrrolo[1,2-c]oxazole]; 706791-71-1; Spiro[cyclopentane-1,3'-[1H,3H]pyrrolo[1,2-c]oxazole]; Pyrrolo[1,2-c]oxazole, 1H,3H-spiro[cyclopentane-1,3'-]; Spiro-cyclopentane-pyrrolooxazole
EINECS	Contact for details

Quality Control

Our Spiro[Cyclopentane-1,3-[1H,3H]Pyrrolo[1,2-C]Oxazole] (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.