Description

5-(2-Fluorophenyl)Nicotinic Acid is a high-purity fluorinated nicotinic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs). This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific fluorinated aromatic motifs into their target structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in the development of new herbicides and pesticides, where the fluorophenyl group can enhance biological activity and metabolic stability.
• Ligand Synthesis: Employed in creating specialized ligands for catalysis and metal-organic frameworks (MOFs) in material science applications.
• Chemical Biology Probes: Acts as a building block for fluorescent tags and molecular probes used in diagnostic and biochemical research.
• Academic & Contract Research: Serves as a valuable reagent for method development and exploratory synthetic chemistry in academic and industrial R&D laboratories.

Basic Information

Product Name	5-(2-Fluorophenyl)Nicotinic Acid
CAS No.	705961-96-2
Molecular Formula	C12H8FNO2
Molecular Weight	217.20 g/mol
Synonyms	2-Fluoro-5-pyridinecarboxylic acid phenyl; 5-(2-Fluorophenyl)-3-pyridinecarboxylic acid; 3-Pyridinecarboxylic acid, 5-(2-fluorophenyl)-; 2-Fluorophenylnicotinic acid; Nicotinic acid, 5-(2-fluorophenyl)-; 5-(o-Fluorophenyl)nicotinic acid
EINECS	Contact for details

Quality Control

Our 5-(2-Fluorophenyl)Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.