Description

(1S)-2'-(Bromomethyl)-[1,1'-Binaphthalene]-2-Carboxaldehyde is a high-purity, chiral binaphthyl derivative featuring both a reactive bromomethyl group and an aldehyde functional group. This compound is a critical chiral building block for the synthesis of sophisticated ligands and catalysts used in asymmetric transformations. It is primarily needed by pharmaceutical R&D and fine chemical synthesis teams developing novel active ingredients and advanced materials.

Application

• Asymmetric Catalyst Synthesis: A key precursor for constructing chiral phosphine, amine, and N-heterocyclic carbene (NHC) ligands used in enantioselective hydrogenation, cross-coupling, and C-H activation reactions.
• Pharmaceutical Intermediate: Serves as a versatile chiral scaffold in the multi-step synthesis of complex drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Material Science Research: Used in the development of chiral polymers, liquid crystals, and molecular recognition systems for sensors and advanced optics.
• Academic & Industrial R&D: Employed in methodological studies and process chemistry for developing new asymmetric synthetic routes.

Basic Information

Item	Details
Product Name	(1S)-2'-(Bromomethyl)-[1,1'-Binaphthalene]-2-Carboxaldehyde
CAS No.	705931-85-7
Molecular Formula	C23H15BrO
Molecular Weight	387.27 g/mol
Synonyms	(S)-2'-(Bromomethyl)-[1,1'-binaphthalene]-2-carboxaldehyde; (S)-2'-(Bromomethyl)-2-naphthalenecarboxaldehyde; (S)-BINOL-Br-CHO; (1S)-2'-(Bromomethyl)-1,1'-binaphthyl-2-carbaldehyde; (S)-2-Formyl-6'-(bromomethyl)-1,1'-binaphthyl; Chiral Binaphthyl Bromoaldehyde; (S)-Bromo-Methyl-BINOL-CHO
EINECS	Contact for details

Quality Control

Our (1S)-2'-(Bromomethyl)-[1,1'-Binaphthalene]-2-Carboxaldehyde is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity (HPLC) and structural confirmation (NMR, IR), to ensure high enantiomeric excess (ee) and chemical integrity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, identity, and chiral purity specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.