Description

Spiro[Cyclopentane-1,3-[1H,3H]Pyrrolo[1,2-C]Oxazol]-1-One, Tetrahydro-, (7As)- (9Ci) is a high-purity, advanced pharmaceutical intermediate characterized by its complex spirocyclic and fused heterocyclic structure. This compound matters as a critical building block in modern organic synthesis, enabling the construction of novel molecular architectures with potential biological activity. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of new active ingredients and for process chemistry optimization.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its complex structure for targeted biological activity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex spirocyclic and polycyclic frameworks in medicinal chemistry.
• Process Chemistry: Utilized in route scouting and scale-up studies for the efficient production of active pharmaceutical ingredients (APIs).
• Chemical Biology Probe Development: Acts as a scaffold for creating molecular probes to study biological pathways and protein interactions.

Basic Information

Product Name	Spiro[Cyclopentane-1,3-[1H,3H]Pyrrolo[1,2-C]Oxazol]-1-One, Tetrahydro-, (7As)- (9Ci)
CAS No.	704905-42-0
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	(7aS)-Tetrahydrospiro[cyclopentane-1,3'-pyrrolo[1,2-c]oxazol]-1'(3'H)-one; Tetrahydrospiro[cyclopentane-1,3'-pyrrolo[1,2-c]oxazol]-1'(3'H)-one, (7aS)-; 704905-42-0; Spiro[cyclopentane-1,3'-[1H,3H]pyrrolo[1,2-c]oxazol]-1'-one, tetrahydro-, (7aS)-; (7aS)-1',2',3',7a'-Tetrahydrospiro[cyclopentane-1,3'-pyrrolo[1,2-c]oxazol]-1'-one
EINECS	Contact for details

Quality Control

Our Spiro[Cyclopentane-1,3-[1H,3H]Pyrrolo[1,2-C]Oxazol]-1-One, Tetrahydro-, (7As)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (7aS)
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.