Description

(R)-(+)-2-Methoxy A-Methylbenzylamine-Hcl CAS NO 704892-60-4 is a high-purity chiral amine derivative, specifically the hydrochloride salt of the (R)-enantiomer. This compound serves as a critical chiral building block and resolving agent in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors who require high optical purity intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs and other therapeutics requiring specific stereochemistry.
• Chiral Resolving Agent: Used to separate racemic mixtures of carboxylic acids or other acidic compounds via diastereomeric salt formation.
• Asymmetric Catalyst Ligand Precursor: Employed in the preparation of chiral ligands for metal-catalyzed asymmetric reactions, such as hydrogenations or additions.
• Agrochemical Synthesis: A building block for creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical and Specialty Material Production: Used in the synthesis of liquid crystals, advanced polymers, and other performance materials where chirality influences properties.
• Academic and Industrial R&D: A valuable reagent for methodological development in organic and medicinal chemistry research.

Basic Information

Product Name	(R)-(+)-2-Methoxy A-Methylbenzylamine-Hcl
CAS No.	704892-60-4
Molecular Formula	C10H16ClNO
Molecular Weight	201.69 g/mol
Synonyms	(R)-(+)-2-Methoxy-α-methylbenzylamine Hydrochloride; (R)-1-(2-Methoxyphenyl)ethylamine Hydrochloride; (R)-O-Methylphenylglycinol Hydrochloride; (R)-2-Methoxy-1-phenylethanamine Hydrochloride; (R)-2-Methoxy-α-methylbenzenemethanamine Hydrochloride; (R)-1-(2-Methoxyphenyl)ethan-1-amine Hydrochloride; (R)-HMPEA HCl; (R)-2-Methoxyamphetamine HCl (pharmacological class reference)
EINECS	Contact for details

Quality Control

Our (R)-(+)-2-Methoxy A-Methylbenzylamine-Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure compliance with high-purity standards, including chiral purity assessment via HPLC. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.