Description

2-Iodo-5-(Trifluoromethyl)Phenylacetic Acid is a high-value, multi-functional chemical building block characterized by its unique combination of an iodine substituent and a trifluoromethyl group on a phenylacetic acid core. This structure makes it a critical intermediate for synthesizing advanced molecules in pharmaceutical and agrochemical research, where it is prized for introducing specific steric and electronic properties. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and life science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of anti-inflammatory and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis for asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials and liquid crystals due to its distinct electronic profile.
• Fluorine Chemistry: An essential reagent for introducing both iodine and fluorine-containing motifs into complex molecular architectures via further functionalization.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	2-Iodo-5-(Trifluoromethyl)Phenylacetic Acid
CAS No.	702641-08-5
Molecular Formula	C9H6F3IO2
Molecular Weight	330.04 g/mol
Synonyms	[2-Iodo-5-(trifluoromethyl)phenyl]acetic acid; 2-Iodo-α-(trifluoromethyl)benzeneacetic acid; (2-Iodo-5-(trifluoromethyl)phenyl)acetic acid; 5-(Trifluoromethyl)-2-iodophenylacetic Acid; 2-Iodo-5-trifluoromethylphenylacetic Acid; α-(2-Iodo-5-(trifluoromethyl)phenyl)acetic acid; Benzeneacetic acid, 2-iodo-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Every batch of 2-Iodo-5-(Trifluoromethyl)Phenylacetic Acid is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.