Description

1-Azabicyclo[2.2.1]Heptane,2,4,6-Trimethyl-,(2R,6S)-Rel-(9Ci) is a high-purity, stereochemically defined bicyclic amine building block of significant interest in advanced organic synthesis. Its rigid, three-dimensional scaffold is crucial for constructing complex molecular architectures with precise spatial orientation, a key requirement in modern pharmaceutical and agrochemical research. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor or scaffold in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets, enzyme inhibitors, and receptor modulators.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or insecticides where its bicyclic structure can impart unique biological activity and stability.
• Catalyst Ligand Synthesis: Acts as a starting material for the preparation of sophisticated chiral ligands used in asymmetric catalysis to create enantiomerically pure compounds.
• Material Science: Employed in the research of advanced polymers or functional materials where its amine functionality and rigid core can influence material properties.
• Academic & Discovery Chemistry: A valuable tool for methodological studies and exploring new chemical space in university and industrial discovery laboratories.

Basic Information

Product Name	1-Azabicyclo[2.2.1]Heptane,2,4,6-Trimethyl-,(2R,6S)-Rel-(9Ci)
CAS No.	700378-37-6
Molecular Formula	C9H17N
Molecular Weight	139.24 g/mol
Synonyms	(2R,6S)-2,4,6-Trimethyl-1-azabicyclo[2.2.1]heptane; rel-(1R,4S)-2,4,6-Trimethyl-2-azabicyclo[2.2.1]heptane; 2-Azabicyclo[2.2.1]heptane, 2,4,6-trimethyl-, (1R,4S)-rel-; Trimethyl-1-azabicyclo[2.2.1]heptane; Bicyclic tertiary amine; 2,4,6-Trimethyl-2-azabicyclo[2.2.1]heptane
EINECS	Contact for details

Quality Control

Our 1-Azabicyclo[2.2.1]Heptane,2,4,6-Trimethyl-,(2R,6S)-Rel-(9Ci) is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC and structural confirmation by NMR and MS, to ensure high chemical and isomeric purity suitable for demanding synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.