Description

p-Methylcalix[6]Arene is a synthetically engineered macrocyclic compound belonging to the calixarene family, characterized by a basket-shaped molecular structure with six phenolic units. This architecture provides a versatile three-dimensional cavity, making it a highly effective host molecule for selective molecular recognition and binding in supramolecular chemistry. It is essential for researchers and manufacturers in advanced material science, pharmaceutical development, and sensor technology who require precise molecular scaffolds for creating functional host-guest systems, catalysts, and separation media.

Application

• Supramolecular Chemistry & Host-Guest Systems: Acts as a foundational building block for constructing molecular capsules, sensors, and switches due to its pre-organized cavity.
• Catalysis & Chemical Synthesis: Serves as a ligand or catalyst support to create selective reaction environments and enhance reaction rates and specificity.
• Separation Science & Extraction: Utilized in the development of stationary phases for chromatography or solid-phase extraction materials for isolating specific ions or organic molecules.
• Material Science & Nanotechnology: Incorporated into the design of advanced polymers, coatings, and nano-structured materials with tailored surface properties.
• Pharmaceutical Research: Investigated for drug delivery applications, where its cavity can be functionalized to encapsulate and transport active pharmaceutical ingredients (APIs).
• Sensor Development: Functionalized to create highly selective chemical sensors for detecting metal ions or small organic molecules in analytical and environmental monitoring.

Basic Information

Product Name	p-Methylcalix[6]Arene
CAS No.	79942-31-7
Molecular Formula	C56H60O6
Molecular Weight	829.07 g/mol
Synonyms	Calix[6]arene, p-methyl-; p-tert-Butylcalix[6]arene, Methylated; Hexameric p-Methylcalixarene; 4-Methylcalix[6]arene; 5,11,17,23,29,35-Hexa-methyl-37,38,39,40,41,42-hexahydroxycalix[6]arene; Octahydroxy[2.2.2.2.2.2]metacyclophane, Methyl Derivative; 1,3,5,7,9,11-Hexa-tert-butyl-2,4,6,8,10,12-hexamethyl[13,33,53,73,93,113]metacyclophane-13,14,15,16,17,18-hexol (alternative IUPAC); Calix-6-arene Methyl Ether Derivative
EINECS	Contact for details

Quality Control

Our p-Methylcalix[6]Arene is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and melting point determination. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment to support your research and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to prevent contamination and minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.