Description

Alpha,Alpha,1-Tris(Phenylmethyl)-2-Pyrrolidinemethanol Hydrochloride is a high-purity organic salt with a complex, multi-branched molecular structure. This compound is valued as a sophisticated chiral intermediate or building block in advanced organic synthesis, particularly for pharmaceuticals and specialty chemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) or receptor-targeted drugs.
• Asymmetric Synthesis Catalyst/ Ligand Precursor: Potential use in developing chiral catalysts or ligands for enantioselective reactions due to its stereogenic centers and nitrogen-containing pyrrolidine moiety.
• Agrochemical Research: Intermediate in the research and development of new generation pesticides or herbicides with specific stereochemical requirements.
• Fine Chemical Synthesis: Used in academic and industrial laboratories for the construction of complex natural product analogs or specialty molecules.
• Material Science Research: Potential monomer or additive in the development of specialized polymers with unique properties.

Basic Information

Product Name	Alpha,Alpha,1-Tris(Phenylmethyl)-2-Pyrrolidinemethanol Hydrochloride
CAS No.	79820-10-3
Molecular Formula	C28H33NO • HCl
Molecular Weight	436.03 g/mol (Free base: 399.57 g/mol)
Synonyms	1,1,1-Tris(phenylmethyl)-2-pyrrolidinemethanol hydrochloride; α,α,1-Tris(benzyl)-2-pyrrolidinemethanol HCl; Tris(benzyl)prolinol hydrochloride; 2-Pyrrolidinemethanol, α,α,1-tris(phenylmethyl)-, hydrochloride; (S)- or (R)-Tris(benzyl)prolinol hydrochloride (stereoisomer specific); Prolinol, Tris(benzyl)-, hydrochloride; 79820-10-3
EINECS	Contact for details

Quality Control

Our Alpha,Alpha,1-Tris(Phenylmethyl)-2-Pyrrolidinemethanol Hydrochloride is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the exacting standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (for enantiomerically pure grade)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.