Description

(S)-2-Hydroxymethylpyrrolidine Hcl is a high-purity chiral building block and intermediate of significant importance in asymmetric synthesis. This compound matters because it provides a versatile scaffold for constructing complex molecules with defined stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) and advanced materials. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for applications in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of various APIs, particularly those targeting neurological and cardiovascular diseases.
• Asymmetric Catalyst Ligand: Used as a precursor for developing novel chiral ligands and organocatalysts in enantioselective reactions.
• Agrochemical Synthesis: Serves as a building block for creating chiral active ingredients in herbicides, fungicides, and insecticides.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & Industrial Research: A valuable reagent for method development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	(S)-2-Hydroxymethylpyrrolidine Hydrochloride
CAS No.	79802-20-3
Molecular Formula	C5H12ClNO
Molecular Weight	137.61 g/mol
Synonyms	(S)-(-)-2-Pyrrolidinemethanol Hydrochloride; (S)-2-(Hydroxymethyl)pyrrolidine Hydrochloride; L-Prolinol Hydrochloride; (S)-Prolinol HCl; (2S)-2-Pyrrolidinylmethanol Hydrochloride; (S)-2-Pyrrolidinylmethanol Hydrochloride; (S)-2-Hydroxymethylpyrrolidine Hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-2-Hydroxymethylpyrrolidine Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and research applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.