Description

Dichloro[(S)-N,n-Dimethyl-1-[(R)-2-(Diphenylphospino)Ferrocenyl]Ethyl-Amine]Palladium(II) is a highly specialized, chiral ferrocenylphosphine palladium complex, recognized as a premier catalyst for asymmetric synthesis. Its core value lies in enabling highly enantioselective cross-coupling and C-H functionalization reactions, which are critical for producing single-isomer pharmaceutical intermediates and fine chemicals. This product is essential for R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• Asymmetric Cross-Coupling Reactions: Enantioselective Suzuki-Miyaura, Negishi, and Buchwald-Hartwig amination reactions for constructing chiral biaryl and C-N bonds.
• Pharmaceutical Intermediate Synthesis: Catalyzing key steps in the production of active pharmaceutical ingredients (APIs) requiring high enantiomeric excess (ee).
• Agrochemical Manufacturing: Synthesis of chiral herbicides, fungicides, and plant growth regulators.
• Asymmetric C-H Activation: Facilitating direct, enantioselective functionalization of C-H bonds, streamlining synthetic routes.
• Fine Chemical Production: Manufacture of specialty chemicals, flavors, fragrances, and liquid crystals where chirality dictates function.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and catalysis research.

Basic Information

Product Name	Dichloro[(S)-N,n-Dimethyl-1-[(R)-2-(Diphenylphospino)Ferrocenyl]Ethyl-Amine]Palladium(II)
CAS No.	79767-72-9
Molecular Formula	C26H27Cl2FeNPPd
Molecular Weight	609.62 g/mol
Synonyms	Josiphos SL-J009-1 Palladium Catalyst; (S)-(-)-1-[(R)-2-(Diphenylphosphino)ferrocenyl]ethyldimethylamine Palladium(II) Dichloride; (S,R)-Josiphos PdCl2; Dichloro[(S)-1-[(R)-2-(Diphenylphosphino)ferrocenyl]ethyldimethylamine]palladium; Pd-J009; Palladium(II) chloride complex with (S)-1-[(R)-2-(Diphenylphosphino)ferrocenyl]ethyldimethylamine; Asymmetric Josiphos-Pd Catalyst
EINECS	Contact for details

Quality Control

Every batch of our chiral palladium catalyst is synthesized and handled under stringent, inert conditions to preserve its catalytic activity and enantiomeric purity. Quality is verified through a comprehensive suite of analytical techniques including NMR, HPLC, and elemental analysis to ensure conformity with rigorous internal specifications. A detailed Certificate of Analysis (COA) providing batch-specific data on purity, metal content, and chiral integrity is supplied with each order.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry place. This compound is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures will degrade its performance.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Palladium (Pd) Content	16.5 - 18.0 %
Solubility	Soluble in dichloromethane, chloroform; slightly soluble in toluene

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.