Description

1,4,7,10,13,16-Hexamethyl-1,4,7,10,13,16-Hexaazacyclooctadecane is a specialized macrocyclic polyamine ligand, a key building block in supramolecular and coordination chemistry. Its value lies in its ability to selectively chelate metal ions, making it an essential precursor for catalysts, magnetic resonance imaging (MRI) contrast agents, and molecular sensors. This high-purity intermediate is critical for researchers and manufacturers in pharmaceuticals, advanced materials science, and diagnostic imaging.

Application

• MRI Contrast Agent Precursor: Serves as a crucial chelating ligand for gadolinium and other lanthanide ions in the synthesis of next-generation magnetic resonance imaging contrast media.
• Catalyst Ligand: Used to create transition metal complexes for homogeneous catalysis in fine chemical and pharmaceutical synthesis.
• Molecular Recognition & Sensing: Acts as a host molecule in supramolecular chemistry for the selective binding and detection of anions or specific metal ions.
• Radiopharmaceuticals: Chelator for radioisotopes (e.g., 64Cu, 68Ga) used in positron emission tomography (PET) imaging and targeted radiotherapy.
• Polymer Modification: Incorporated into polymer backbones to impart metal-binding properties for creating functional materials like ion-exchange resins or smart polymers.
• Research & Development: A fundamental reagent in academic and industrial R&D for exploring new coordination compounds and host-guest systems.

Basic Information

Product Name	1,4,7,10,13,16-Hexamethyl-1,4,7,10,13,16-Hexaazacyclooctadecane
CAS No.	79676-97-4
Molecular Formula	C18H42N6
Molecular Weight	342.57 g/mol
Synonyms	Hexamethyl-1,4,7,10,13,16-hexaazacyclooctadecane; Me6[18]aneN6; 1,4,7,10,13,16-Hexamethyl-1,4,7,10,13,16-hexaazacyclooctadecane; Hexamethylcyclen; TM-18-ane-N6; Hexamethyl-1,4,7,10,13,16-hexaaza-18-crown-6; N,N',N'',N''',N'''',N'''''-Hexamethyl-1,4,7,10,13,16-hexaazacyclooctadecane
EINECS	Contact for details

Quality Control

Our production of 1,4,7,10,13,16-Hexamethyl-1,4,7,10,13,16-Hexaazacyclooctadecane adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.