Description

n-Propanoylmannosamine is a chemically modified monosaccharide derivative, specifically an N-acylated mannosamine analog. This compound is a critical building block and precursor in the synthesis of complex carbohydrates, glycoconjugates, and sialic acid analogs. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those developing novel glycotherapeutics, diagnostic probes, and metabolic labeling tools. The high-purity material enables precise control in glycosylation reactions and metabolic engineering studies.

Application

• Glycobiology Research: A key precursor for the chemical and enzymatic synthesis of sialylated oligosaccharides and glycoproteins.
• Metabolic Oligosaccharide Engineering (MOE): Used as a metabolic substrate to label cell-surface glycans with bioorthogonal chemical handles for imaging and targeting.
• Pharmaceutical Intermediates: Serves as a vital intermediate in the production of sialic acid-based drug candidates and vaccine components.
• Diagnostic Development: Employed in the creation of diagnostic assays and probes that target sialic acid-dependent biological recognition events.
• Enzyme Substrate Studies: Acts as a substrate for sialyltransferases and other glycosyltransferases in mechanistic and inhibition studies.
• Bioconjugation: Facilitates the site-specific modification of proteins and nanoparticles through its reactive functional groups.

Basic Information

Product Name	n-Propanoylmannosamine
CAS No.	79624-37-6
Molecular Formula	C9H17NO6
Molecular Weight	235.24 g/mol
Synonyms	ManNProp; N-Propanoyl-D-mannosamine; D-Mannosamine, N-propanoyl-; 2-Acetamido-2-deoxy-D-mannose N-propanoyl derivative; N-Propionylmannosamine; Acetamido-deoxy-mannose propanoyl; Propanoylamino mannose; Glycobiology building block 79624-37-6
EINECS	Contact for details

Quality Control

Our n-Propanoylmannosamine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and specific optical rotation measurement to ensure identity, potency, and consistency. We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with research and cGMP-grade specifications as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Keep the container tightly sealed in a desiccated environment after opening.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.