Description

5-Aminolevulinic Acid Methyl Ester Hydrochloride is a key chemical intermediate and active pharmaceutical ingredient (API) derivative of 5-aminolevulinic acid (5-ALA). This compound matters for its role as a direct precursor in the biosynthesis of porphyrins, making it a critical component in photodynamic therapy (PDT) research and diagnostic applications. It is primarily needed by pharmaceutical R&D laboratories, manufacturers of diagnostic agents, and academic institutions focused on developing novel cancer treatments and studying heme biosynthesis pathways.

Application

• Photodynamic Therapy (PDT) Research: Serves as a prodrug for the in-situ generation of the photosensitizer protoporphyrin IX (PpIX) in cancer cell studies.
• Diagnostic Agent Synthesis: Used in the development and production of agents for the fluorescence-guided detection and resection of malignant tissues.
• Biochemical Research: A vital tool for studying the heme biosynthesis pathway, enzyme kinetics, and porphyrin metabolism in biological systems.
• Pharmaceutical Intermediate: Acts as a key building block in the synthesis of more complex porphyrin-based therapeutic compounds.
• Agricultural Research: Investigated for its potential use as a biodegradable herbicide or plant growth regulator due to its role in chlorophyll synthesis.
• Cosmeceutical Development: Explored in topical formulations for skin condition treatments, leveraging its cellular metabolic activity.

Basic Information

Product Name	5-Aminolevulinic Acid Methyl Ester Hydrochloride
CAS No.	79416-27-6
Molecular Formula	C6H12N2O3 • HCl
Molecular Weight	196.63 g/mol (Free base: 160.17)
Synonyms	5-ALA Methyl Ester Hydrochloride; Methyl 5-Aminolevulinate Hydrochloride; 5-Aminolevulinic Acid Methyl Ester HCl; 5-ALA-ME HCl; Methyl Aminolevulinate Hydrochloride; 5-Amino-4-oxopentanoic Acid Methyl Ester Hydrochloride; Metvixia® API Intermediate; 79416-27-6
EINECS	Contact for details

Quality Control

Our 5-Aminolevulinic Acid Methyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade standards suitable for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.