Description

Ethyl 7-Chloro-1-Ethyl-6-Fluoro-4-Oxo-1,4-Dihydro[1,8]Naphthyridine-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial importance. This compound serves as a critical building block in the synthesis of novel quinolone and naphthyridine-based active pharmaceutical ingredients (APIs). It is essential for research and manufacturing organizations in the global pharmaceutical and fine chemical sectors seeking reliable, high-quality intermediates for antibiotic development.

Application

• Key Intermediate for Antibiotic Synthesis: Primarily used in the research and production of next-generation fluoroquinolone and naphthyridone antibacterial agents.
• Pharmaceutical R&D: Serves as a crucial scaffold for medicinal chemists exploring new structures with enhanced antimicrobial activity and improved safety profiles.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in controlled synthesis processes to produce bulk APIs for final drug formulations.
• Process Chemistry & Scale-Up: Used in process optimization and pilot-scale production for new drug candidates under development.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development, quality control, and regulatory submissions.
• Fine Chemical Synthesis: Utilized in the synthesis of complex, fluorinated heterocyclic compounds for various specialty chemical applications.

Basic Information

Product Name	Ethyl 7-Chloro-1-Ethyl-6-Fluoro-4-Oxo-1,4-Dihydro[1,8]Naphthyridine-3-Carboxylate
CAS No.	79286-86-5
Molecular Formula	C₁₃H₁₂ClFN₂O₃
Molecular Weight	298.70 g/mol
Synonyms	7-Chloro-1-ethyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid ethyl ester; Ethyl 7-chloro-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylate; 1,8-Naphthyridine-3-carboxylic acid, 7-chloro-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-, ethyl ester; 79286-86-5; AB-FQNX Intermediate; Quinolone Derivative Intermediate
EINECS	Contact for details

Quality Control

Our Ethyl 7-Chloro-1-Ethyl-6-Fluoro-4-Oxo-1,4-Dihydro[1,8]Naphthyridine-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.