Description

1-Azabicyclo[2.2.2]Octane-3-Methanol Hydrochloride is a high-purity, quinuclidine-based organic salt with significant synthetic utility. This compound serves as a versatile and valuable building block in advanced organic synthesis, particularly for constructing complex nitrogen-containing molecular architectures. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for neurological and anti-infective agents.
• Ligand Synthesis: Used to prepare sophisticated nitrogen-donor ligands for catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Serves as a building block for developing new crop protection compounds and herbicides.
• Chemical Biology Probe Development: Employed in the creation of molecular probes for studying enzyme function and biological pathways.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and asymmetric synthesis.
• Fine Chemical Production: Used in the multi-step synthesis of specialty chemicals and performance materials.

Basic Information

Product Name	1-Azabicyclo[2.2.2]Octane-3-Methanol Hydrochloride
CAS No.	79221-75-3
Molecular Formula	C8H16ClNO
Molecular Weight	177.67 g/mol
Synonyms	3-(Hydroxymethyl)quinuclidine hydrochloride; Quinuclidin-3-ylmethanol hydrochloride; 3-Quinuclidinol hydrochloride (related); 1-Azabicyclo[2.2.2]octan-3-ylmethanol hydrochloride; 3-(Hydroxymethyl)-1-azabicyclo[2.2.2]octane hydrochloride; 3-Quinuclidinemethanol hydrochloride; (1-Azabicyclo[2.2.2]oct-3-yl)methanol hydrochloride
EINECS	Contact for details

Quality Control

Our 1-Azabicyclo[2.2.2]Octane-3-Methanol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and production use. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.