Description

n-(9H-Fluoren-9-Ylacetyl)Tryptophan is a specialized, high-purity synthetic amino acid derivative, specifically engineered for advanced research and development applications. This compound is valued for its role as a key building block and protecting group intermediate in sophisticated organic synthesis, particularly in peptide chemistry. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on developing novel therapeutic peptides and biochemical probes.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the solid-phase and solution-phase synthesis of complex peptides and peptidomimetics for drug discovery.
• Bioconjugation Reagent: Used for the site-specific labeling and modification of peptides and proteins in biochemical research.
• Fluorenylmethyloxycarbonyl (Fmoc) Chemistry: Acts as an Fmoc-protected tryptophan derivative, essential for peptide synthesis using Fmoc/t-Bu strategies.
• Proteomics Research: Employed in the study of protein structure, function, and interactions, particularly where tryptophan analogs are required.
• Academic & Industrial R&D: A vital reagent for synthetic organic chemists in universities and corporate R&D departments developing new bioactive compounds.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	n-(9H-Fluoren-9-Ylacetyl)Tryptophan
CAS No.	79189-73-4
Molecular Formula	C28H24N2O3
Molecular Weight	436.50 g/mol
Synonyms	Fmoc-Tryptophan; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-tryptophan; N-Fluoren-9-ylmethoxycarbonyl-L-tryptophan; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]tryptophan; L-Tryptophan, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-; Fmoc-Trp-OH; Fmoc-L-Trp; Fmoc-TRP
EINECS	Contact for details

Quality Control

Our n-(9H-Fluoren-9-Ylacetyl)Tryptophan is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and comprehensive identification tests. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Optical Rotation	-20.0° to -24.0° (c=1 in DMF)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.