Description

D-Proline, 4-Hydroxy-1-Nitroso-, cis- (9Ci) is a specialized, non-proteinogenic amino acid derivative featuring a unique nitroso group on the proline ring. This compound is of significant interest in advanced organic synthesis and pharmaceutical research, serving as a key chiral building block and a precursor for complex molecular architectures. It is primarily utilized by research institutions and chemical manufacturers focused on developing novel pharmaceuticals, agrochemicals, and sophisticated chiral ligands or catalysts.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in protease inhibitor design.
• Asymmetric Synthesis: Employed as a building block or chiral auxiliary in stereoselective organic reactions to construct complex molecules with high enantiomeric purity.
• Biochemical Research: Used in studies of enzyme inhibition, peptide mimetics, and as a probe to investigate biological pathways involving proline metabolism.
• Agrochemical Development: Serves as a precursor in the synthesis of advanced, target-specific herbicides or plant growth regulators.
• Coordination Chemistry: Acts as a ligand for metal complexes in catalytic systems or material science applications due to its chelating potential.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and for creating proprietary compound libraries.

Basic Information

Item	Details
Product Name	D-Proline, 4-Hydroxy-1-Nitroso-, cis- (9Ci)
CAS No.	79171-52-1
Molecular Formula	C5H8N2O3
Molecular Weight	144.13 g/mol
Synonyms	(2R,4R)-4-Hydroxy-1-nitrosopyrrolidine-2-carboxylic acid; cis-4-Hydroxy-1-nitroso-D-proline; D-4-Hydroxy-1-nitroso-proline; 1-Nitroso-4-hydroxy-D-proline; (9CI) D-Proline, 4-hydroxy-1-nitroso-, cis-; 79171-52-1; (R,R)-4-Hydroxy-1-nitrosoproline
EINECS	Contact for details

Quality Control

Our D-Proline, 4-Hydroxy-1-Nitroso-, cis- (9Ci) is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification (IR, NMR). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive nature, handling should be performed under subdued light or in amber glass containers to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.