Description

Quinoline, 5-Bromo-6-Fluoro-1,2,3,4-Tetrahydro-2-Methyl- is a high-value, multi-functional heterocyclic building block, specifically a substituted tetrahydroquinoline derivative. This compound is engineered to serve as a critical intermediate in advanced organic synthesis, offering precise bromo and fluoro substitution patterns for structure-activity relationship (SAR) studies and molecular diversification. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients, including kinase inhibitors and other biologically relevant small molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting specific enzyme pathways where halogenated quinoline scaffolds are active.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated structure for enhanced bioactivity and environmental stability.
• Material Science: Serves as a building block for advanced organic electronic materials, such as charge-transport layers or light-emitting components, due to its conjugated quinoline core.
• Chemical Biology & Probe Development: Employed in the design of fluorescent probes or molecular tags for imaging and diagnostic applications.
• Academic & Contract Research: Essential for synthetic methodology development and medicinal chemistry projects in university and CRO laboratories.

Basic Information

Product Name	Quinoline, 5-Bromo-6-Fluoro-1,2,3,4-Tetrahydro-2-Methyl-
CAS No.	79085-71-5
Molecular Formula	C10H11BrFN
Molecular Weight	244.10 g/mol
Synonyms	5-Bromo-6-fluoro-2-methyl-1,2,3,4-tetrahydroquinoline; 2-Methyl-5-bromo-6-fluoro-1,2,3,4-tetrahydroquinoline; 5-Bromo-6-fluoro-2-methyl-1,2,3,4-tetrahydroquinoline; 1,2,3,4-Tetrahydro-5-bromo-6-fluoro-2-methylquinoline; Quinoline, 5-bromo-6-fluoro-1,2,3,4-tetrahydro-2-methyl-; 79085-71-5
EINECS	Contact for details

Quality Control

Our Quinoline, 5-Bromo-6-Fluoro-1,2,3,4-Tetrahydro-2-Methyl- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.