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2,2'-Diamino-1-1'-Binaphthyl CAS NO 79082-81-8
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CAS No.:79082-81-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2,2'-Diamino-1,1'-binaphthyl is a high-purity, axially chiral diamine compound, also known as BINAM. This compound is a crucial chiral building block and ligand precursor in asymmetric synthesis, valued for its ability to induce high enantioselectivity in catalytic reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality chiral intermediates for developing novel active ingredients and functional molecules.
Application
- Asymmetric Catalysis: Serves as a privileged precursor for synthesizing chiral phosphine, diimine, and salen ligands used in hydrogenation, coupling, and cycloaddition reactions.
- Pharmaceutical Intermediates: A key chiral scaffold in the research and development of enantiomerically pure drugs, particularly for central nervous system (CNS) and cardiovascular targets.
- Chiral Resolution Agents: Used to derivatize racemic mixtures for analytical separation or to prepare chiral stationary phases for HPLC.
- Advanced Material Synthesis: Employed in the creation of chiral polymers, metal-organic frameworks (MOFs), and supramolecular structures with specific optical or electronic properties.
- Agrochemical Development: Utilized in the synthesis of chiral active ingredients for herbicides, fungicides, and pesticides where specific stereochemistry is critical for activity and environmental safety.
- Academic & Industrial R&D: A fundamental reagent for methodological development in organic chemistry and process chemistry optimization.
Basic Information
| Product Name | 2,2'-Diamino-1,1'-binaphthyl |
| CAS No. | 79082-81-8 |
| Molecular Formula | C₂₀H₁₆N₂ |
| Molecular Weight | 284.36 g/mol |
| Synonyms | (±)-1,1'-Binaphthyl-2,2'-diamine; BINAM; 2,2'-Diamino-[1,1'-binaphthalene]-4,4'-diol (Note: This is a common related compound, often searched); rac-1,1'-Binaphthyl-2,2'-diamine; 2,2'-Diamino-1,1'-binaphthalene; [1,1'-Binaphthalene]-2,2'-diamine; DNBA |
| EINECS | Contact for details |
Quality Control
Every batch of our 2,2'-Diamino-1,1'-binaphthyl undergoes rigorous analytical testing to ensure it meets the stringent purity requirements for chiral synthesis and pharmaceutical research. Our standard quality protocol includes assessment by HPLC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess where applicable. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your internal quality standards.
Storage
Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to light and oxidation, prolonged exposure to air and light should be avoided to maintain product integrity.
Specification
| Item | Specification |
|---|---|
| Appearance | Off-white to light yellow crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Melting Point | 245 - 250 °C |
| Loss on Drying | ≤ 0.5% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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