Description

Bastadin 5 is a biologically active marine natural product, specifically a brominated tyrosine-derived alkaloid isolated from marine sponges. This compound is of significant interest in biochemical and pharmacological research due to its potent and selective activity as an inhibitor of the IP3 receptor, a key calcium channel in cellular signaling pathways. Researchers in pharmaceutical development, marine biotechnology, and cell biology utilize Bastadin 5 CAS NO 79067-75-7 as a critical tool compound for studying calcium homeostasis, muscle contraction mechanisms, and for screening novel therapeutic agents.

Application

• Biochemical Research: Used as a selective and potent inhibitor of the inositol 1,4,5-trisphosphate (IP3) receptor to study intracellular calcium release and signaling cascades.
• Pharmacological Studies: Serves as a reference standard and tool compound in drug discovery programs targeting calcium-dependent processes for conditions like cardiovascular diseases and neurological disorders.
• Marine Natural Product Research: Acts as a representative compound for studying the biosynthesis, ecological role, and chemical diversity of brominated alkaloids from marine organisms.
• Cell Biology: Employed to investigate the role of calcium ions in cellular functions such as muscle contraction, neurotransmitter release, and apoptosis.
• High-Throughput Screening (HTS): Utilized as a control or probe in assay development for identifying new modulators of calcium channel activity.

Basic Information

Product Name	Bastadin 5
CAS No.	79067-75-7
Molecular Formula	C30H22Br4N4O6
Molecular Weight	862.04 g/mol
Synonyms	Bastadin-5; Bastadin 5; 5,5'-[1,12-Dodecanediylbis(iminocarbonyloxy-3,1-phenyleneimino-2,1-ethanediyl)]bis[2-bromo-6-hydroxy-4-methylbenzamide]; Ianthelline F; IP3 Receptor Inhibitor Bastadin 5
EINECS	Contact for details

Quality Control

Our Bastadin 5 is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot is characterized using advanced analytical techniques, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, analytical methods, and results is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation. For short-term use, store desiccated at 2-8°C.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.