Description

2,2,2-Trifluoro-1-(1,2,3,4-tetrahydroquinolin-1-yl)ethan-1-one is a high-purity trifluoroacetylated heterocyclic compound, serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive trifluoroacetyl group tethered to a tetrahydroquinoline scaffold, enabling the introduction of fluorinated motifs to enhance the metabolic stability and bioavailability of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, including potential kinase inhibitors and central nervous system (CNS) active agents.
• Agrochemical Synthesis: Used in the research and production of advanced, fluorinated pesticides and herbicides to improve efficacy and environmental profile.
• Material Science Research: Serves as a precursor for specialty polymers and advanced organic materials requiring fluorinated aromatic components.
• Chemical Biology Probes: Utilized in the design of fluorinated probes and tags for studying biological mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring specific, complex fluorinated heterocycles.

Basic Information

Product Name	2,2,2-Trifluoro-1-(1,2,3,4-tetrahydroquinolin-1-yl)ethan-1-one
CAS No.	79066-90-3
Molecular Formula	C11H10F3NO
Molecular Weight	229.20 g/mol
Synonyms	1-(1,2,3,4-Tetrahydroquinolin-1-yl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(1,2,3,4-tetrahydro-1-quinolinyl)ethanone; N-Trifluoroacetyltetrahydroquinoline; 1-Trifluoroacetyl-1,2,3,4-tetrahydroquinoline; Trifluoroacetic acid tetrahydroquinoline-1-yl ester; 79066-90-3; TFTHQ
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-(1,2,3,4-tetrahydroquinolin-1-yl)ethan-1-one is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our commitment to quality supports compliance with cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.