Description

2-(Trifluoromethyl)Quinoline-4-Carbaldehyde is a high-value, multi-functional heterocyclic building block characterized by its quinoline core and reactive aldehyde group. This compound is essential for advanced organic synthesis, enabling the construction of complex molecular architectures for research and development. It is primarily sought after by pharmaceutical, agrochemical, and material science industries for applications in drug discovery, ligand synthesis, and the development of specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders and infectious diseases.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, leveraging the trifluoromethyl group for enhanced bioactivity and stability.
• Ligand & Catalyst Synthesis: Serves as a versatile scaffold for creating nitrogen-containing ligands used in transition metal catalysis and coordination chemistry.
• Material Science: Employed in the research of organic semiconductors, fluorescent dyes, and photoactive materials due to its conjugated quinoline structure.
• Chemical Biology Probes: Utilized to develop molecular probes and sensors for studying biological processes and enzyme inhibition.
• Custom Synthesis & Scale-up: A critical starting material for contract research organizations (CROs) and CDMOs for custom synthesis projects.

Basic Information

Product Name	2-(Trifluoromethyl)Quinoline-4-Carbaldehyde
CAS No.	78946-17-5
Molecular Formula	C11H6F3NO
Molecular Weight	225.17 g/mol
Synonyms	2-(Trifluoromethyl)-4-quinolinecarboxaldehyde; 4-Quinolinecarboxaldehyde, 2-(trifluoromethyl)-; Quinoline-4-carbaldehyde, 2-(trifluoromethyl)-; 2-Trifluoromethylquinoline-4-carboxaldehyde; 2-Trifluoromethyl-4-quinolinecarbaldehyde; 2-Trifluoromethyl-4-formylquinoline; 4-Formyl-2-(trifluoromethyl)quinoline
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)Quinoline-4-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Handle and store in accordance with all applicable local and international regulations.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.