Description

H-D-Arg-Ome 2Hcl is a protected derivative of the amino acid L-Arginine, specifically the hydrochloride salt of its D-enantiomer methyl ester. This high-purity building block is critical for the synthesis of complex peptides and bioactive molecules where stereochemical control is paramount. It is primarily utilized by research institutions and pharmaceutical companies engaged in advanced peptide chemistry, proteomics, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) for introducing the D-arginine residue with a protected side chain.
• Biochemical Research: Serves as a standard or reagent in proteomics research, enzyme substrate studies, and metabolic pathway investigation.
• Asymmetric Synthesis: Employed in the preparation of non-natural amino acids and complex organic molecules requiring specific stereochemistry.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for method development and quality control.

Basic Information

Product Name	H-D-Arg-Ome 2Hcl
CAS No.	78851-84-0
Molecular Formula	C7H18Cl2N4O2
Molecular Weight	261.15 g/mol
Synonyms	D-Arginine methyl ester dihydrochloride; Methyl D-argininate dihydrochloride; H-D-Arg-OMe•2HCl; (R)-Methyl 2-amino-5-guanidinopentanoate dihydrochloride; D-Arg-OMe•2HCl; Methyl (2R)-2-amino-5-(diaminomethylideneamino)pentanoate dihydrochloride; 78851-84-0; D-Arg methyl ester HCl
EINECS	Contact for details

Quality Control

Our H-D-Arg-Ome 2Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.