Description

6-Hydroxy-6,9,10,11-Tetrahydro-Chromeno[4,3-B]Quinolin-8-One is a high-purity, advanced pharmaceutical intermediate belonging to the chromenoquinoline class of heterocyclic compounds. This compound matters as a critical building block for the synthesis of novel, complex molecules with potential biological activity, offering researchers and manufacturers a reliable and well-characterized starting material. It is primarily needed by pharmaceutical R&D laboratories and fine chemical producers engaged in developing new therapeutic agents, particularly in areas requiring sophisticated fused-ring systems.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system or oncological pathways.
• Organic Synthesis Building Block: Used in research-scale and pilot-scale reactions to construct complex chromenoquinoline scaffolds for structure-activity relationship (SAR) studies.
• Medicinal Chemistry Research: Employed in the discovery and optimization of new chemical entities (NCEs) due to its unique fused heterocyclic structure.
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in pharmaceutical analysis.
• Chemical Biology Probe Development: Acts as a core structure for developing molecular probes to study biological processes and protein interactions.

Basic Information

Product Name	6-Hydroxy-6,9,10,11-Tetrahydro-Chromeno[4,3-B]Quinolin-8-One
CAS No.	78831-30-8
Molecular Formula	C₁₆H₁₃NO₃
Molecular Weight	267.28 g/mol
Synonyms	6-Hydroxy-6,9,10,11-tetrahydrochromeno[4,3-b]quinolin-8-one; 8H-Chromeno[4,3-b]quinolin-8-one, 6,9,10,11-tetrahydro-6-hydroxy-; 6-Hydroxy-6,9,10,11-tetrahydro-8H-chromeno[4,3-b]quinolin-8-one; Chromeno[4,3-b]quinolin-8-one, 6,9,10,11-tetrahydro-6-hydroxy-; 78831-30-8 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 6-Hydroxy-6,9,10,11-Tetrahydro-Chromeno[4,3-B]Quinolin-8-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.