Description

2,3-Dihydro-3-(Iodomethyl)-Benzofuran CAS NO 78739-83-0 is a versatile benzofuran derivative featuring an iodomethyl functional group, making it a valuable synthetic intermediate in advanced organic chemistry. This compound is particularly significant for its role in constructing complex molecular architectures through cross-coupling and substitution reactions. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders or inflammation.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging the benzofuran scaffold for biological activity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic electronic materials.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Negishi couplings to form carbon-carbon bonds.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands for catalysis or as a scaffold for catalyst design in asymmetric synthesis.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological processes and target identification.

Basic Information

Product Name	2,3-Dihydro-3-(Iodomethyl)-Benzofuran
CAS No.	78739-83-0
Molecular Formula	C9H9IO
Molecular Weight	260.07 g/mol
Synonyms	3-(Iodomethyl)-2,3-dihydrobenzofuran; 2,3-Dihydro-3-iodomethylbenzofuran; Benzofuran, 2,3-dihydro-3-(iodomethyl)-; 3-Iodomethyl-2,3-dihydrobenzofuran; 78739-83-0; AI3-52711
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-3-(Iodomethyl)-Benzofuran is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.