Description

1-Methyl-3-Pyrrolidinone Hydrochloride is a versatile organic salt derivative of N-Methyl-2-pyrrolidone (NMP), widely recognized for its utility as a high-purity intermediate and reagent in advanced chemical synthesis. Its primary value lies in providing a controlled, reactive form of the pyrrolidinone moiety, which is crucial for constructing complex molecular architectures in regulated environments. This compound is essential for research and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable building blocks for active pharmaceutical ingredients (APIs), ligands, and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those containing the pyrrolidinone pharmacophore.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where specific nitrogen-containing heterocycles are required.
• Chemical Research & Development: Serves as a versatile reagent in organic synthesis for introducing the N-methylpyrrolidinone group under controlled acidic conditions.
• Ligand and Catalyst Preparation: Employed in the preparation of specialized ligands for metal catalysis and coordination chemistry.
• Specialty Polymer Modification: Acts as a functional monomer or modifying agent in the synthesis of polymers with specific solubility or binding properties.

Basic Information

Product Name	1-Methyl-3-Pyrrolidinone Hydrochloride
CAS No.	78635-85-5
Molecular Formula	C5H10ClNO
Molecular Weight	135.59 g/mol
Synonyms	1-Methyl-3-pyrrolidinone HCl; 3-Pyrrolidinone, 1-methyl-, hydrochloride; N-Methyl-3-pyrrolidinone hydrochloride; 1-Methylpyrrolidin-3-one hydrochloride; 3-Oxo-1-methylpyrrolidinium chloride
EINECS	Contact for details

Quality Control

Our 1-Methyl-3-Pyrrolidinone Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via techniques such as HPLC, NMR, and titration. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your internal quality standards and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.