Description

Estradiol-17Beta 3-Carboranylmethyl Ether is a chemically modified derivative of the natural hormone estradiol, where a carboranyl group is introduced via an ether linkage at the 3-position. This strategic modification is designed to impart unique properties, such as enhanced lipophilicity and potential for boron neutron capture therapy (BNCT) applications, making it a valuable intermediate for advanced pharmaceutical research. It is primarily utilized by research institutions and pharmaceutical developers focused on oncology, hormone therapy, and novel drug delivery systems.

Application

• Boron Neutron Capture Therapy (BNCT) Research: Serves as a key boron-containing precursor for developing targeted cancer therapeutics.
• Pharmaceutical Intermediate: Used in the synthesis of novel steroidal compounds with potential therapeutic applications.
• Hormone Receptor Studies: Acts as a specialized ligand for investigating estrogen receptor interactions and signaling pathways.
• Radiopharmaceutical Development: Explored as a building block for creating labeled compounds for diagnostic imaging or targeted radiotherapy.
• Advanced Material Science: Investigated for incorporation into polymers or delivery systems due to its unique carborane structure.
• Academic & Industrial R&D: Employed in chemical and biological research to study structure-activity relationships (SAR) of modified steroids.

Basic Information

Product Name	Estradiol-17Beta 3-Carboranylmethyl Ether
CAS No.	78328-63-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	17β-Estradiol 3-(Carboranylmethyl) Ether; 3-[(1,2-Dicarba-closo-dodecaboran-1-yl)methoxy]estra-1,3,5(10)-triene-17β-ol; Estradiol 3-Carboranylmethyl Ether; E2-Carboranyl Ether; Boronated Estradiol Derivative
EINECS	Contact for details

Quality Control

Our Estradiol-17Beta 3-Carboranylmethyl Ether is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and structural confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.