Description

3-Hydroxy-5-Nitrobenzoic Acid is a versatile aromatic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a phenolic hydroxyl and a nitro group ortho to a carboxylic acid, makes it a valuable intermediate for creating complex molecules with specific electronic and steric properties. This chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop active ingredients, dyes, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Synthesis: Used in the development of advanced herbicides, pesticides, and plant growth regulators due to its bioactive nitroaromatic core.
• Dye and Pigment Manufacturing: Serves as a starting material for azo dyes and other complex colorants, contributing to color fastness and specific hue properties.
• Ligand and Chelating Agent Preparation: The functional groups allow for the creation of chelating ligands used in catalysis and metal ion sequestration.
• Polymer Modification: Employed to introduce nitro and carboxylic acid functionalities into polymer chains, altering physical and chemical properties.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new organic reactions and synthesizing complex heterocyclic compounds.

Basic Information

Product Name	3-Hydroxy-5-Nitrobenzoic Acid
CAS No.	78238-14-9
Molecular Formula	C7H5NO5
Molecular Weight	183.12 g/mol
Synonyms	5-Nitro-3-hydroxybenzoic acid; 3-Hydroxy-5-nitrobenzoic acid; Benzoic acid, 3-hydroxy-5-nitro-; 5-Nitrosalicylic acid (ambiguous, but sometimes used); 3-Carboxy-5-nitrophenol; 5-Nitro-m-hydroxybenzoic acid; 3-Hydroxy-5-nitro-benzoic acid; 5-Nitro-3-hydroxy-benzoic acid
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-5-Nitrobenzoic Acid is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets precise specifications. Certificates of Analysis (COA) documenting all critical parameters are available for every shipment, providing full traceability and compliance assurance for your quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	215°C - 220°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.