Description

1,1'-Binaphthalene, 3,3'-Dibromo-5,5',6,6',7,7',8,8'-Octahydro-2,2'-Dimethoxy-, (1R)- is a high-value, chiral binaphthyl derivative, a crucial building block in advanced organic synthesis. Its significance lies in its rigid, three-dimensional structure which is essential for creating asymmetric environments in catalysis and molecular recognition. This compound is primarily needed by research and development teams in the pharmaceutical and fine chemical industries for applications in ligand synthesis, chiral resolution, and the development of novel materials.

Application

• Chiral Ligand Synthesis: Serves as a core scaffold for constructing sophisticated ligands used in asymmetric catalysis, including hydrogenation and cross-coupling reactions.
• Pharmaceutical Intermediates: A key precursor in the synthesis of complex, optically active drug candidates and active pharmaceutical ingredients (APIs).
• Material Science Research: Used in the development of chiral polymers, liquid crystals, and other functional materials with specific optical properties.
• Catalyst Development: Integral for creating novel organocatalysts and transition metal catalysts for stereoselective synthesis.
• Analytical Chemistry: Employed as a chiral selector or stationary phase modifier in chromatography for enantiomer separation.
• Academic & Industrial R&D: A vital tool for chemists exploring new synthetic methodologies and stereochemistry.

Basic Information

Product Name	1,1'-Binaphthalene, 3,3'-Dibromo-5,5',6,6',7,7',8,8'-Octahydro-2,2'-Dimethoxy-, (1R)-
CAS No.	78229-12-6
Molecular Formula	C22H24Br2O2
Molecular Weight	488.24 g/mol
Synonyms	(R)-3,3'-Dibromo-2,2'-dimethoxy-1,1'-binaphthyl-5,5',6,6',7,7',8,8'-octahydro; (R)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-octahydro-2,2'-dimethoxy-1,1'-binaphthyl; (R)-H8-3,3'-Dibromo-2,2'-dimethoxy-1,1'-binaphthyl; (R)-Octahydro-3,3'-dibromo-2,2'-dimethoxy-1,1'-binaphthyl; (1R)-3,3'-Dibromo-5,5',6,6',7,7',8,8'-octahydro-2,2'-dimethoxy-1,1'-binaphthalene; Chiral Binaphthyl Derivative; BINOL Derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing lot-specific results are available upon request. Our quality management system is designed to meet the stringent requirements of research and pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.