Description

4-Fluoro-2-(Methylsulfonyl)Nitrobenzene is a high-value fluorinated aromatic building block characterized by its unique combination of electron-withdrawing substituents. This compound matters for its critical role in facilitating complex molecular transformations in advanced chemical synthesis. Pharmaceutical, agrochemical, and specialty chemical R&D teams need it as a key intermediate for developing novel active ingredients, particularly in the creation of sulfonamide-based molecules and other heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those containing sulfonyl and nitro functional groups for targeted biological activity.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides where the fluorine atom enhances bioavailability and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic electronic materials.
• Dye & Pigment Intermediate: Employed in the synthesis of complex, high-performance colorants and photographic chemicals.
• Cross-Coupling Reactions: Acts as a versatile substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing complex biaryl systems.
• Chemical Research & Development: A valuable reagent for exploring new reaction pathways and synthesizing libraries of compounds for screening in various industries.

Basic Information

Product Name	4-Fluoro-2-(Methylsulfonyl)Nitrobenzene
CAS No.	78228-02-1
Molecular Formula	C7H6FNO4S
Molecular Weight	219.19 g/mol
Synonyms	1-Fluoro-4-(methylsulfonyl)-2-nitrobenzene; 2-Nitro-4-fluoro-1-(methylsulfonyl)benzene; 4-Fluoro-2-nitro-1-(methylsulfonyl)benzene; 4-Fluoro-2-(methylsulfonyl)-1-nitrobenzene; 2-(Methylsulfonyl)-4-fluoronitrobenzene; Benzene, 1-fluoro-4-(methylsulfonyl)-2-nitro-; (4-Fluoro-2-nitrophenyl)(methyl)sulfone
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-(Methylsulfonyl)Nitrobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and production use. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.