Description

Toluene-4-13C is a stable isotope-labeled derivative of toluene, where the carbon atom at the 4-position is the carbon-13 (13C) isotope. This compound is essential as an internal standard and tracer in advanced analytical chemistry, enabling precise quantitative analysis and metabolic pathway studies. It is primarily required by research institutions, pharmaceutical developers, and analytical laboratories engaged in mass spectrometry, nuclear magnetic resonance (NMR) spectroscopy, and environmental fate studies.

Application

• Internal Standard for Quantitative Analysis: Used in Gas Chromatography-Mass Spectrometry (GC-MS) and Liquid Chromatography-Mass Spectrometry (LC-MS) for the accurate quantification of toluene and related compounds in complex matrices.
• Metabolic Tracer in Biomedical Research: Employed to study the biotransformation and metabolic pathways of toluene in pharmacological and toxicological research.
• NMR Spectroscopy Solvent & Reference: Serves as a chemical shift reference or a labeled solvent in 13C NMR experiments for structural elucidation.
• Environmental Tracing: Applied in environmental science to track the degradation, movement, and fate of toluene contaminants in soil and water systems.
• Isotope Dilution Mass Spectrometry (IDMS): A critical component in high-precision IDMS methods, which are considered a primary measurement technique.
• Chemical Reaction Mechanism Studies: Utilized to investigate reaction mechanisms and kinetics in organic synthesis and catalysis where the 13C label can be followed.

Basic Information

Product Name	Toluene-4-13C
CAS No.	78218-02-7
Molecular Formula	C7H8 (13CH3C6H4)
Molecular Weight	93.15 g/mol
Synonyms	4-13C-Toluene; Toluene-ring-13C; Methyl-13C-benzene; [4-13C]Toluene; 13C Labeled Toluene; Toluene (4-13C); Toluene, 4-13C-; p-13C-Toluene
EINECS	Contact for details

Quality Control

Our Toluene-4-13C is produced and handled under strict quality protocols to ensure the highest isotopic and chemical purity for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and solvent residue profiles. We adhere to relevant industry standards for high-purity reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong oxidizers. Due to its highly volatile nature, ensure containers are securely sealed to prevent evaporation and concentration of vapors.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms to structure
Isotopic Enrichment (13C)	≥ 99 atom %
Chemical Purity (GC)	≥ 99.5%
Water Content (KF)	≤ 0.05%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.