Description

Difluoromethane (13C, 99%) is a stable isotope-labeled analog of the common refrigerant and chemical intermediate, difluoromethane. This compound, with the CAS registry number 27572-45-8, is enriched with carbon-13 at the central carbon atom, providing a non-radioactive tracer for advanced analytical and research applications. It is essential for scientists and engineers in the fields of atmospheric chemistry, refrigerant development, and reaction mechanism studies who require precise molecular tracking. The high isotopic purity (99%) ensures reliable and unambiguous results in mass spectrometry and NMR spectroscopy.

Application

• Analytical Reference Standard: Used as an internal standard or calibrant in Gas Chromatography-Mass Spectrometry (GC-MS) and Liquid Chromatography-Mass Spectrometry (LC-MS) for the quantification of difluoromethane and related compounds in complex matrices.
• Atmospheric Science Research: Employed in tracer studies to model the environmental fate, transport, and degradation pathways of hydrofluorocarbons (HFCs) in the atmosphere.
• Reaction Mechanism Elucidation: Serves as a crucial tool in chemical reaction studies, allowing researchers to track the specific carbon atom through synthetic pathways or catalytic cycles using 13C NMR spectroscopy.
• Pharmaceutical & Metabolic Research: Utilized in the development and analysis of pharmaceutical compounds where fluorinated moieties are present, aiding in metabolism and pharmacokinetics studies.
• Refrigerant & Propellant R&D: Acts as a labeled compound in the research and development of next-generation, low-global-warming-potential refrigerants and aerosol propellants.

Basic Information

Product Name	Difluoromethane (13C, 99%)
CAS No.	27572-45-8
Molecular Formula	13CH2F2
Molecular Weight	53.02 g/mol
Synonyms	Carbon-13 Labeled Difluoromethane; [13C]-Difluoromethane; HFC-32 (13C); Methylene Fluoride-13C; Freon 32 (13C); R-32 (13C); 13C-Labeled Methylene Difluoride; (13C)Methane, difluoro-
EINECS	Contact for details

Quality Control

Our Difluoromethane (13C, 99%) is manufactured and handled under stringent quality systems to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and gas composition. We adhere to relevant industry standards for stable isotope-labeled compounds, ensuring data integrity for your critical analytical work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its gaseous state, ensure the cylinder or container valve is securely closed when not in use and store upright in a secure location. Recommended storage temperature is 15-25°C.

Specification

Item	Specification
Appearance	Colorless gas
Identification (IR)	Conforms to reference spectrum
13C Isotopic Enrichment	≥ 99%
Chemical Purity (GC)	≥ 99%
Water Content	< 10 ppm
Non-condensable gases	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.