Description

N6-Benzyl-2’,3’-Isopropylideneadenosine is a key protected nucleoside derivative, widely utilized as a critical synthetic intermediate in pharmaceutical research and development. Its primary value lies in enabling the selective modification and functionalization of the adenosine scaffold, which is fundamental for creating novel bioactive compounds. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors focused on nucleoside-based drug discovery, including antiviral and anticancer agent development.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel adenosine receptor agonists/antagonists and other nucleoside-based therapeutics.
• Antiviral Drug Research: Used in the development and structural modification of potential antiviral agents targeting viral polymerases.
• Medicinal Chemistry: Serves as a protected precursor for introducing the N6-benzyladenosine moiety into more complex molecular architectures during lead optimization.
• Biochemical Research: Employed in studies investigating adenosine signaling pathways and enzyme-substrate interactions where a protected, functionalized adenosine analog is required.
• Fine Chemical Synthesis: Acts as a specialized intermediate for the custom synthesis of high-value, labeled, or modified nucleosides for diagnostic and research applications.

Basic Information

Product Name	N6-Benzyl-2’,3’-Isopropylideneadenosine
CAS No.	78188-38-2
Molecular Formula	C20H23N5O4
Molecular Weight	397.43 g/mol
Synonyms	N6-Benzyladenosine 2',3'-Isopropylidene acetal; 2',3'-O-Isopropylidene-N6-benzyladenosine; 6-(Benzylamino)-9-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]purine 2',3'-acetonide; N6-Benzyl-2',3'-O-isopropylideneadenosine; 6-Benzylaminopurine riboside 2',3'-acetonide; N6-Benzyl-2',3'-O-(1-methylethylidene)adenosine; Bn-Ado-2',3'-acetonide
EINECS	Contact for details

Quality Control

Our N6-Benzyl-2’,3’-Isopropylideneadenosine is manufactured under strict quality control protocols to ensure high chemical purity and batch-to-batch consistency, suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemical intermediates, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.