Description

4-Bromo-3-Nitrophenol is a halogenated nitrophenol derivative that serves as a versatile and critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both bromine and nitro substituents on the phenolic ring, makes it a valuable building block for constructing complex molecules. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring halogenated aromatic scaffolds.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and pesticides, where the bromo and nitro groups contribute to biological activity.
• Dye and Pigment Manufacturing: Serves as a starting material for the production of azo dyes and other complex colorants.
• Ligand and Catalyst Development: Employed in research to create novel ligands for metal catalysis and coordination chemistry.
• Material Science Research: Used in the synthesis of monomers and polymers with specific electronic or photonic properties.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.

Basic Information

Product Name	4-Bromo-3-Nitrophenol
CAS No.	78137-76-5
Molecular Formula	C6H4BrNO3
Molecular Weight	218.01 g/mol
Synonyms	3-Nitro-4-bromophenol; 4-Bromo-3-nitrophenol; Phenol, 4-bromo-3-nitro-; 4-Brom-3-nitrophenol; 4-Bromo-3-nitro-phenol; 78137-76-5; NSC 406696
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Nitrophenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.