Description

4-tert-Butylcalix[6]arene is a synthetic macrocyclic compound belonging to the calixarene family, characterized by a basket-shaped molecular structure with six phenolic units linked by methylene bridges. This unique three-dimensional architecture provides a versatile molecular platform for host-guest chemistry, enabling selective binding and complexation of various ions and neutral molecules. It is a critical intermediate and building block for researchers and manufacturers in advanced material science, supramolecular chemistry, and the development of specialized sensors and separation technologies.

Application

• Supramolecular Chemistry & Host-Guest Systems: Acts as a molecular receptor or building block for constructing complex molecular assemblies, capsules, and frameworks.
• Ion-Selective Sensors & Electrodes: Utilized as an ionophore in the development of chemical sensors and potentiometric electrodes for detecting specific metal cations.
• Catalysis & Enzyme Mimics: Serves as a scaffold for constructing nanoreactors and artificial enzymes due to its well-defined cavity that can encapsulate substrates.
• Separation Science: Employed in the synthesis of stationary phases for chromatography or as an extractant in liquid-liquid extraction processes for selective ion separation.
• Advanced Material Synthesis: Used as a precursor for functionalized surfaces, dendrimers, polymers, and other nanomaterials with tailored properties.
• Pharmaceutical & Biomedical Research: Investigated for potential applications in drug delivery systems, molecular recognition of biomolecules, and as a component in diagnostic tools.

Basic Information

Product Name	4-tert-Butylcalix[6]arene
CAS No.	78092-53-2
Molecular Formula	C66H84O6
Molecular Weight	973.36 g/mol
Synonyms	p-tert-Butylcalix[6]arene; Calix[6]arene, 4-tert-butyl-; 4-(1,1-Dimethylethyl)calix[6]arene; 5,11,17,23,29,35-Hexa-tert-butyl-37,38,39,40,41,42-hexahydroxycalix[6]arene; 37,38,39,40,41,42-Hexahydroxy-5,11,17,23,29,35-hexa-tert-butylcalix[6]arene; 1,3,5-Tris[(4-tert-butyl-2-hydroxy-5-methylphenyl)methyl]benzene (common misnomer for structure); Hexameric p-tert-butylphenol-formaldehyde cyclic oligomer
EINECS	Contact for details

Quality Control

Our 4-tert-Butylcalix[6]arene is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity assessment, NMR and IR for structural confirmation, and melting point determination. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment to support your research and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.