Description

2-Chloro-6-(Trifluoromethyl)Quinoline is a high-value, multi-functional heterocyclic building block distinguished by its unique halogenated and fluorinated structure. This compound is essential for the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its specific substitution pattern enables precise molecular design. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, leveraging the trifluoromethyl group for enhanced biological activity and metabolic stability.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as ligands for OLEDs and charge-transport molecules.
• Ligand and Catalyst Development: The quinoline nitrogen and chloro group make it a versatile precursor for creating complex chelating ligands in catalysis.
• Fluorinated Compound Research: Critical for studying structure-activity relationships (SAR) in medicinal and agrochemical chemistry due to the presence of the CF3 group.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for use in bespoke synthesis projects requiring specialized fluorinated heterocycles.

Basic Information

Product Name	2-Chloro-6-(Trifluoromethyl)Quinoline
CAS No.	78060-56-7
Molecular Formula	C10H5ClF3N
Molecular Weight	231.60 g/mol
Synonyms	6-(Trifluoromethyl)-2-chloroquinoline; 2-Chloro-6-trifluoromethylquinoline; Quinoline, 2-chloro-6-(trifluoromethyl)-; 2-Chloro-6-(trifluoromethyl)chinolin; 2-Chloro-6-(trifluorométhyl)quinoléine
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-6-(Trifluoromethyl)Quinoline is manufactured under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.